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Hemodynamic and central blood pressure differences between carvedilol and valsartan added to lisinopril at rest and during exercise stress
20 January 2012
Joseph L. Izzo, Minesh Rajpal, Shaila Karan, Sirisha Srikakarlapudi, Peter J. Osmond
Abstract: There is little information about the hemodynamic and exercise-response implications of renin-angiotensin system blocker combinations. After a 3-week lisinopril (L; 40 mg/day) run-in, carved...
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The effects of blood pressure control levels on the renoprotection of type 2 diabetic patients without overt proteinuria
26 December 2011
Takashi Uzu, Yasuo Kida, Atsushi Yamauchi, Shinji Kume, Keiji Isshiki, Shin-ichi Araki, Daisuke Koya, Masakazu Haneda, Atsunori Kashiwagi, Hiroshi Maegawa, Ryuichi Kikkawa
Abstract: Background: There is little evidence regarding the target blood pressure level in patients with type 2 diabetes mellitus without overt proteinuria. Methods and Results: We followed 608 Japan...
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Association between circulating specific leukocyte types and incident chronic kidney disease: the Atherosclerosis Risk in Communities (ARIC) study
04 November 2011
Niu Tian, Alan D. Penman, R. Davis Manning, Michael F. Flessner, Anthony R. Mawson
Abstract: Progressive renal fibrosis is a characteristic of all the diseases that cause renal failure and is invariably accompanied by a prominent leukocyte infiltration in the kidney. The goal of thi...
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Efficacy and safety of triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in study participants with hypertension and diabetes: a subpopulation analysis of the TRINITY study
28 October 2011
Steven G. Chrysant, Joseph L. Izzo, Dean J. Kereiakes, Thomas Littlejohn, Suzanne Oparil, Michael Melino, James Lee, Victor Fernandez, Reinilde Heyrman
Abstract: Background: Most patients with hypertension and diabetes require two or more antihypertensive agents to achieve the recommended blood pressure (BP) goal of <130/80 mm Hg. This prespecifie...
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