Journal of the American Society of Hypertension
Volume 3, Issue 4 , Pages 238-244, July 2009

A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study

  • Renata N. Freitas, MBiochem, PhD

      Affiliations

    • Departmento de Nutrição Clinica e Social, School of Nutrition and Núcleo de Pesquisas em Ciências Biológicas, Federal University of Ouro Preto, Ouro Preto, Brazil
    • Medical Research Council Center for Nutritional Epidemiology in Cancer Prevention and Survival, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
    • Corresponding Author InformationCorresponding author: Renata N. Freitas, MBiochem, PhD, DENCS/ENUT/UFOP, Campus Universitario, Morro de Cruzeiro, Ouro Preto, MG, 35400000, Brazil. Tel: +55 31 35591838; fax: +55 31 55591828.
  • ,
  • Kay-Tee Khaw, MBBChir

      Affiliations

    • Medical Research Council Center for Nutritional Epidemiology in Cancer Prevention and Survival, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
    • EPIC Norfolk, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
  • ,
  • Kelvin Wu, PhD

      Affiliations

    • Medical Research Council Dunn Human Nutrition Unit, University of Cambridge, Cambridge, United Kingdom
  • ,
  • Richard Bowman, BSc

      Affiliations

    • Medical Research Council Dunn Human Nutrition Unit, University of Cambridge, Cambridge, United Kingdom
  • ,
  • Hannah Jeffery, MBiochem

      Affiliations

    • Medical Research Council Dunn Human Nutrition Unit, University of Cambridge, Cambridge, United Kingdom
  • ,
  • Robert Luben, BSc

      Affiliations

    • EPIC Norfolk, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
  • ,
  • Nick J. Wareham, MBBS, PhD

      Affiliations

    • EPIC Norfolk, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
    • Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom
  • ,
  • Sheila A. Bingham, PhD

      Affiliations

    • Medical Research Council Center for Nutritional Epidemiology in Cancer Prevention and Survival, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
    • EPIC Norfolk, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
    • Medical Research Council Dunn Human Nutrition Unit, University of Cambridge, Cambridge, United Kingdom

Received 10 March 2009; accepted 28 May 2009.

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 This study was supported by Programme Grants from the Medical Research Council, London, United Kingdom; Cancer Research, London, United Kingdom; and Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq, Brazil (a fellowship to Dr. Freitas).

 Conflict of interest: none.

PII: S1933-1711(09)00066-7

doi:10.1016/j.jash.2009.05.001

Journal of the American Society of Hypertension
Volume 3, Issue 4 , Pages 238-244, July 2009