Journal of the American Society of Hypertension
Volume 3, Issue 3 , Pages 192-200 , May 2009

Transient stenotic-like occlusions as a possible mechanism for renovascular hypertension due to aneurysm

  • Linden A. Heflin

      Affiliations

    • University of Oklahoma Bioengineering Center
    • Department of Chemical, Biological and Materials Engineering, University of Oklahoma; Norman, Oklahoma, USA
    • ,
  • Carrie B. Street

      Affiliations

    • Department of Chemical, Biological and Materials Engineering, University of Oklahoma; Norman, Oklahoma, USA
    • ,
  • Dimitrios V. Papavassiliou, PhD

      Affiliations

    • Department of Chemical, Biological and Materials Engineering, University of Oklahoma; Norman, Oklahoma, USA
    • ,
  • David C. Kem, MD

      Affiliations

    • Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
    • ,
  • Dee H. Wu, PhD

      Affiliations

    • Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
    • ,
  • Edgar A. O'Rear, PhD

      Affiliations

    • University of Oklahoma Bioengineering Center
    • Department of Chemical, Biological and Materials Engineering, University of Oklahoma; Norman, Oklahoma, USA
    • Corresponding Author InformationCorresponding author: Edgar A. O'Rear, PhD, Francis W. Winn Professor, School of Chemical, Biological and Materials Engineering, University of Oklahoma, T-335 Sarkeys Energy Center, 100 East Boyd Street, Norman, Oklahoma 73019. Tel: 405-325-4379; fax: 405-325-5813.

Received 1 December 2008 ,Accepted 13 February 2009.

References 

  1. Goldblatt H, Lynch J, Hanzal R, Summerville W. Studies on experimental hypertension I. The production of persistent elevation of systolic blood pressure by means of renal ischemia. J Exp Med. 1934;59:347–379
  2. Hartman R, Kawashima A, King B. Evaluation of renal causes of hypertension. Radiol Clin North Am. 2003;41:909–929
  3. Serter S, Oran I, Parildar M, Memis A. Fibromuscular dysplasia-related renal artery stenosis associated with aneurysm: successive endovascular therapy. Cardiovasc Intervent Radiol. 2007;30:297–299
  4. Al-Harbi A, Chaudry T, Linjawi T, Alfarayh O, Al-Sohaibani H, Al-Shaibani K, et al. Renal artery stenosis in renal transplantation presentation and management. Saudi J Kidney Dis Transpl. 1998;9:22–26
  5. Kem D, Lyons D, Wenzl J, Halverstadt D, Yu X. Renin-dependent hypertension caused by nonfocal stenotic aberrant renal arteries: proof of a new syndrome. Hypertension. 2005;46:380–385
  6. Hackam D, Spence J, Garg A, Textor S. Role of renin-angiotensin system blockade in atherosclerotic renal artery stenosis and renovascular hypertension. Hypertension. 2007;50:998–1003
  7. Young D. Fluid mechanics of arterial stenoses. J Biomech Eng. 1979;101:185–196
  8. Shalman E, Barak C, Dgany E, Noskowitcz H, Einav S, Rosenfeld M. Pressure-based simultaneous CFR and FFR measurements: understanding the physiology of a stenosed vessel. Comput Biol Med. 2001;31:353–363
  9. Phillips J. Pathogenesis of hypertension in renal failure: role of the sympathetic nervous system and renal afferents. Clin Exp Pharmacol Physiol. 2005;32:415–418
  10. Yim P, Cebral J, Weaver A, Lutz R, Soto O, Vasbinder B, et al. Estimation of the differential pressure at renal artery stenoses. Magn Reson Med. 2004;51:969–977
  11. Tham G, Ekelund L, Herrlin K, Lindstedt E, Olin T, Bergentz S. Renal artery aneurysms. Natural history and prognosis. Ann Surg. 1983;197:348–352
  12. Gallagher K, Phelan M, Stern T, Bartlett S. Repair of complex renal artery aneurysms by laparoscopic nephrectomy with ex vivo repair and autotransplantation. J Vasc Surg. 2008;48:1408–1413
  13. Buchanan J, Kleinstreuer C, Hyun S, Truskey G. Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aorta. J Biomech. 2003;36:1185–1196
  14. Liang F, Yamaguchi R, Liu H. Fluid dynamics in normal and stenosed human renal arteries: an experimental and computational study. J Biomech Sci Eng. 2006;1:171–182
  15. Steinman D. Image-based computational fluid dynamics modeling in realistic arterial geometries. Ann Biomed Eng. 2002;30:483–497
  16. Taylor C, Hughes T, Zarins C. Finite element modeling of three-dimensional pulsatile flow in the abdominal aorta: relevance to atherosclerosis. Ann Biomed Eng. 1998;26:975–987
  17. Castro MA, Putman CM, Cebral JR. Patient-specific computational modeling of cerebral aneurysms with multiple avenues of flow from 3D rotational angiography images. Acad Radiol. 2006;13:811–821
  18. Dempere-Marco L, Oubel E, Castro M, Putman C, Frangi A, Cebral J. CFD analysis incorporating the influence of wall motion: application to intracranial aneurysms. Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2006;9:438–445
  19. Hoi Y, Woodward S, Kim M, Taulbee D, Meng H. Validation of CFD simulations of cerebral aneurysms with implication of geometric variations. J Biomech Eng. 2006;128:844–851
  20. Shojima M, Oshima M, Takagi K, Torii R, Hayakawa M, Katada K, et al. Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke. 2004;35:2500–2505
  21. Cooney D. Biomedical Engineering Principles: An Introduction to Fluid, Heat, and Mass Transport Processes. New York, New York: Marcel Dekker; 1976;
  22. Ku D. Blood flow in arteries. Ann Rev Fluid Mech. 1997;29:399–434
  23. Yamaguchi T, Ishikawa T, Tsubota K, Imai Y, Nakamura M, Fukui T. Computational blood flow analysis—new trends and methods. J Biomech Sci Eng. 2006;1:29–50
  24. Perktold K, Resch M, Peter R. Three-dimensional numerical analysis of pulsatile flow and wall shear stress in the carotid artery bifurcation. J Biomech. 1991;24:409–420
  25. Rindt C, Steenhoven A. Unsteady flow in a rigid 3-D model of the carotid artery bifurcation. J Biomech Eng. 1996;118:90–96
  26. Frauenfelder T, Lotfey M, Boehm T, Wildermuth S. Computational fluid dynamics: hemodynamic changes in abdominal aortic aneurysm after stent-graft implantation. Cardiovasc Intervent Radiol. 2006;29:613–623
  27. Nguyen K, Clark C, Chancellor T, Papavassiliou D. Carotid geometry effects on blood flow and on risk for vascular disease. J Biomech. 2008;41:11–19
  28. Henke P, Cardneau J, Welling T, Upchurch G,, Wakefield T, Jacobs L, et al. Renal artery aneurysms: a 35-year clinical experience with 252 aneurysms in 168 patients. Ann Surg. 2001;234:454–462discussion 462–3
  29. Degertekin M, Bayrak F, Mutlu B, Gurses B, Guran S, Demirtas E. Images in cardiovascular medicine. Large renal artery aneurysm treated with stent graft. Circulation. 2006;113:e848–e849
  30. Hubert J, Pairolero P, Kazmier F. Solitary renal artery aneurysm. Surgery. 1980;88:557–565
  31. Lumsden A, Salam T, Walton K. Renal artery aneurysm: a report of 28 cases. Cardiovasc Surg. 1996;4:185–189
  32. Bastounis E, Pikoulis E, Georgopoulos S, Alexiou D, Leppaniemi A, Boulafendis D. Surgery for renal artery aneurysms: a combined series of two large centers. Eur Urol. 1998;33:22–27
  33. Hupp T, Allenberg J, Post K, Roeren T, Meier M, Clorius J. Renal artery aneurysm: surgical indications and results. Eur J Vasc Surg. 1992;6:477–486
  34. Bui B, Oliva V, Leclerc G, Courteau M, Harel C, Plante R, et al. Renal artery aneurysm: treatment with percutaneous placement of a stent-graft. Radiology. 1995;195:181–182
  35. Bisschops R, Popma J, Meyerovitz M. Treatment of fibromuscular dysplasia and renal artery aneurysm with use of a stent-graft. J Vasc Interv Radiol. 2001;12:757–760
  36. Tan W, Chough S, Saito J, Wholey M, Eles G. Covered stent for renal artery aneurysm. Catheter Cardiovasc Interv. 2001;52:106–109
  37. Pershad A, Heuser R. Renal artery aneurysm: successful exclusion with a stent graft. Catheter Cardiovasc Interv. 2004;61:314–316
  38. Castillo O, Peacock L, Diaz M, Orellana S, Urena R. Case report: laparoscopic repair of saccular renal-artery aneurysm. J Endourol. 2006;20:260–261
  39. Gross C, Krämer J, Weingärtner O, Uhlich F, Luft F, Waigand J, et al. Determination of renal arterial stenosis severity: comparison of pressure gradient and vessel diameter. Radiology. 2001;220:751–756
  40. Stansby G, Hilson A, Hamilton G. Renovascular hypertension secondary to renal artery aneurysm detected by captopril-renography. Eur J Vasc Surg. 1991;5:343–346

 Conflict of interest: none.

PII: S1933-1711(09)00013-8

doi: 10.1016/j.jash.2009.02.004

Journal of the American Society of Hypertension
Volume 3, Issue 3 , Pages 192-200 , May 2009

Article Tools

* Image Usage & Resolution