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Journal of the American Society of Hypertension
Volume 3, Issue 3
, Pages 184-191
, May 2009
Aldosterone receptor antagonism reduces urinary C-reactive protein excretion in angiotensin II–infused, hypertensive rats
References
- C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992. Circulation. 1999;99:237–242
- . C-reactive protein, inflammation, and coronary risk. Med Clin North Am. 2000;84:149–161
- . C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in Women. N Engl J Med. 2000;342:836–843
- . C-reactive protein and the risk of developing hypertension. JAMA. 2003;290:2945–2951
- C-reactive protein in heart failure: prognostic value and the effect of valsartan. Circulation. 2005;112:1428–1434
- C-reactive protein causes downregulation of vascular angiotensin subtype 2 receptors and systolic hypertension in mice. Circulation. 2007;115:1020–1028
- Significant association of C-reactive protein with arterial stiffness in treated non-diabetic hypertensive patients. Atherosclerosis. 2007;192:401–406
- . The effects of extended-release metoprolol succinate on C-reactive protein levels in persons with hypertension. J Clin Hypertens. 2006;8:257–260
- Complement activation in angiotensin II-induced organ damage. Circ Res. 2005;97:716–724
- . Angiotensin II-induced C-reactive protein generation: inflammatory role of vascular smooth muscle cells in atherosclerosis. Atherosclerosis. 2007;193:292–298
- . Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. Kidney Int. 2003;63:1791–1800
- . Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension. 1998;31:451–458
- . Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart. Endocrinology. 2002;143:4828–4836
- . Review of aldosterone- and angiotensin II-induced target organ damage and prevention. Cardiovasc Res. 2004;61:63–70
- . Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension. 2002;40:504–510
- . Evidence of fetal C-reactive protein urinary excretion in early gestation. Obstet Gynecol. 2003;101:1062–1063
- . C-reactive protein: purification by affinity chromatography and physicochemical characterization. J Immunol Met. 1978;23:285–295
- . Specificity of C-reactive protein for choline phosphate residues of pneumococcal C-polysaccharide. Proc Soc Exp Biol Med. 1971;136:612–614
- . Effects of eplerenone on heart and kidney in two-kidney, one-clip rats. Am J Nephrol. 2004;24:54–60
- Eplerenone shows renoprotective effect by reducing LOX-1-mediated adhesion molecule, PKC{epsilon}-MAPK-p90RSK, and rho-kinase pathway. Hypertension. 2005;45:538–544
- Aldosterone: a mediator of myocardial necrosis and renal arteriopathy. Endocrinology. 2000;141:3871–3878
- Eplerenone reduces oxidative stress and enhances eNOS in SHR: vascular functional and structural consequences. Antioxid Redox Signaling. 2005;7:1294–1301
- Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation. Arterioscler Thromb Vasc Biol. 2006;26:917–921
- . Aldosterone receptor antagonism exacerbates intrarenal angiotensin II augmentation in Ang II-dependent hypertension. Am J Physiol Renal Physiol. 2007;293:F139–F147
- . Comparative studies on the binding properties of human and rabbit C-reactive proteins. J Immunol. 1980;124:1396–1402
- . Primary structure of human C-reactive protein. Proc Natl Acad Sci. 1977;74:3148–3151
- . Human C-reactive protein: expression, structure, and function. Mol Immunol. 2001;38:189–197
- . C-reactive protein: a nontraditional serum marker of cardiovascular risk. Cardiovasc Pathol. 2007;16:14–21
- . High-sensitive C-reactive protein, tumor necrosis factor [alpha], and cardiovascular risk factors before and after weight loss in obese children. Metabolism. 2005;54:1155–1161
- . Comparison of interleukin-6 and C-reactive protein for the risk of developing hypertension in women. Hypertension. 2007;49:304–310
- . The novel role of C-reactive protein in cardiovascular disease: risk marker or pathogen. Int J Cardiol. 2006;106:291–297
- . Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs. Circulation. 2001;103:2531–2534
- . Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation. 2000;102:2165–2168
- . C-reactive protein-mediated low-density lipoprotein uptake by macrophages: implications for atherosclerosis. Circulation. 2001;103:1194–1197
- . C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases. Med Hypoth. 2004;62:499–506
- . C-reactive protein: linking inflammation to cardiovascular complications. Circulation. 2001;104:974–975
- . Chronic angiotensin II infusion promotes atherogenesis in low-density lipoprotein receptor -/- mice. Ann N Y Acad Sci. 1999;892:108–118
- . Angiotensin II administration to atherosclerotic mice increases macrophage uptake of oxidized LDL: a possible role for interleukin-6. Arterioscler Thromb Vasc Biol. 2001;21:1464–1469
- Angiotensin II amplifies macrophage-driven atherosclerosis. Arterioscler Thromb Vasc Biol. 2004;24:2143–2148
- Angiotensin II type 1 receptor blocker telmisartan suppresses superoxide production and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice. Atherosclerosis. 2006;186:402–410
- . Yee K-M, Struthers AD. Effect of spironolactone on C-reactive protein levels in patients with heart disease. Int J Cardiol. 2007;117:282–284
- Role of angiotensin II type 1 receptor in the regulation of cellular adhesion molecules in atherosclerosis. Am Heart J. 2001;142:248–253
- . Effects of angiotensin II receptor blockade with valsartan on pro-inflammatory cytokines in patients with essential hypertension. J Cardiovasc Pharmacol. 2005;46:735–739
- Early markers of inflammation in a high angiotensin II state—results of studies in Bartter's/Gitelman's syndromes. Nephrol Dial Transplant. 2006;21:1697–1701
- . Oxidative stress in hypertension and chronic kidney disease: role of angiotensin II. Semin Nephrol. 2004;24:101–114
- . Enhanced superoxide generation modulates renal function in Ang II-induced hypertensive rats. Am J Physiol Renal Physiol. 2006;290:F80–F86
- . Role of oxidative stress in angiotensin-induced hypertension. Am J Physiol Regul Integr Comp Physiol. 2003;284:R893–R912
- . Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease. Am J Cardiol. 2006;98:121–128
- . Inflammation and angiotensin II. Int J Biochem Cell Biol. 2003;35:881–900
- . Ang II-induced cardiac molecular and cellular events: role of aldosterone. Am J Physiol Heart Circ Physiol. 2006;291:H336–H343
- Reactive oxygen species-dependent hypertension in dopamine D2 receptor-deficient mice. Hypertension. 2007;49:672–678
- Systemic and regional hemodynamic responses to tempol in angiotensin II-infused hypertensive rats. Hypertension. 2001;37:77–83
Dr. Ortiz was partially supported by an National Institutes of Health (NIH) National Research Service Award (NRSA) (F32 HL076985) from National Heart, Lung & Blood Institute (NHLBI). Research was supported by the NHLBI Grant HL 26371 (Dr Navar), NIH Center of Biomedical Research Excellence (COBRE) Grant P20 RR017659 from the Institutional Award (IdeA) Program of the National Center for Research Resources, the Millennium Health Excellence Fund from the Louisiana Board of Regents, the University of California, and the University of California, Merced Graduate Research Committee Award.
PII: S1933-1711(09)00008-4
doi: 10.1016/j.jash.2009.01.003
© 2009 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.
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Journal of the American Society of Hypertension
Volume 3, Issue 3
, Pages 184-191
, May 2009
