Journal of the American Society of Hypertension
Volume 3, Issue 2 , Pages 141-149 , March 2009

Familial burden of hypertension and its effect on blood pressure levels, insulin resistance, and intracellular ions in Greek offspring

Received 14 August 2008 ,Accepted 7 October 2008.

References 

  1. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens. 2003;21:1011–1053
  2. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005;365:217–223
  3. Tozawa M, Oshiro S, Iseki C, Sesoko S, Higashiuesato Y, Tana T, et al. Family history of hypertension and blood pressure in a screened cohort. Hypertens Res. 2001;24:93–98
  4. Fuentes RM, Notkola IL, Shemeikka S, Tuomilehto J, Nissinen A. Familial aggregation of body mass index: a population-based family study in Eastern Finland. Horm Metab Res. 2002;34:406–410
  5. Castellano M. Diogenes in the 2000s: searching for hypertension genes. J Hypertens. 2004;22:1081–1083
  6. Lascaux-Lefebvre V, Ruidavets JB, Arveiler D, Amouyel P, Haas B, Cottel D, et al. Influence of parental history of hypertension on blood pressure. J Hum Hypertens. 1999;13:631–636
  7. Rutherford PA. Genetic influences in human hypertension. J Hypertens. 2003;21:19–22
  8. Shirakawa T, Ozono R, Kasagi F, Oshima T, Kamada N, Kambe M. Differential impact of family history on age-associated increase in the prevalence of hypertension and diabetes in male Japanese workers. Hypertens Res. 2006;29:81–87
  9. Ward R. Familial aggregation and genetic epidemiology of blood pressure. In:  Laragh JH,  Brenner BM editor. Hypertension: Pathophysiology, Diagnosis, and Management. 2nd ed.. New York, New York: Raven Press; 1995;p. 67–88
  10. Rebbeck TR, Turner ST, Sing CF. Probability of having hypertension: Effects of sex, history of hypertension in parents, and other risk factors. J Clin Epidemiol. 1996;49:727–734
  11. Winnicki M, Somers VK, Dorigatti F, Longo D, Santonastaso M, Mos L, et al. Lifestyle, family history and progression of hypertension. J Hypertens. 2006;24:1479–1487
  12. DeFronzo RA, Ferrannini E. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care. 1991;14:173–194
  13. Zavaroni I, Mazza S, Dall'Aglio E, Gasparini P, Passeri M, Reaven GM. Prevalence of hyperinsulinaemia in patients with high blood pressure. J Intern Med. 1992;231:235–240
  14. Sowers JR, Draznin B. Insulin, cation metabolism and insulin resistance. J Basic Clin Physiol Pharmacol. 1998;9:223–233
  15. Byyny RL, LoVerde M, Lloyd S, Mitchell W, Draznin B. Cytosolic calcium and insulin resistance in elderly patients with essential hypertension. Am J Hypertens. 1992;5:459–464
  16. Resnick LM. Cellular ions in hypertension, insulin resistance, obesity, and diabetes: a unifying theme. J Am Soc Nephrol. 1992;3:78–85
  17. Zemel MB. Nutritional and endocrine modulation of intracellular calcium: implications in obesity, insulin resistance and hypertension. Mol Cell Biochem. 1998;188:129–136
  18. Wu X, Kan D, Province M, Quertermous T, Rao DC, Chang C, et al. An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP). Am J Hypertens. 2006;19:122–127
  19. Chu SL, Zhu DL, Xiong MM, Wang GL, Zhang WZ, Zhou HF, et al. Linkage analysis of twelve candidate gene loci regulating water and sodium metabolism and membrane ion transport in essential hypertension. Hypertens Res. 2002;25:635–639
  20. Lijnen P, M'Buyamba-Kabangu JR, Fagard R, Staessen J, Amery A. Erythrocyte concentrations and transmembrane fluxes of sodium and potassium in essential hypertension: role of intrinsic and environmental factors. Cardiovasc Drugs Ther. 1990;4:321–333
  21. Ohno Y, Suzuki H, Yamakawa H, Nakamura M, Saruta T. Insulin sensitivity and calcium homeostasis in young, lean, and normotensive male subjects. Hypertens Res. 2000;23:433–440
  22. Skrabal F, Hamberger L, Ledochowski M. Inherited salt sensitivity in normotensive humans as a cause of essential hypertension: a new concept. J Cardiovasc Pharmacol. 1984;6:S215–S223
  23. Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents: a working group report from the National High Blood Pressure Education Program. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents. Pediatrics. 1996;98:649–658
  24. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003;289:2560–2572
  25. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–419
  26. Smith E, Samuels PD. Abnormalities in the sodium pump of erythrocytes from patients with hyperparathyroidism. Clin Sci. 1970;38:49–61
  27. Goldstein IB, Shapiro D, Guthrie D. Ambulatory blood pressure and family history of hypertension in healthy men and women. Am J Hypertens. 2006;19:486–491
  28. Pechére-Bertschi A, Burnier M. Female sex hormones, salt, and blood pressure regulation. Am J Hypertens. 2004;17:994–1001
  29. Van Hooft IMS, Grobbee DE, Frolich M, Pols HAP, Hofman A. Alterations in calcium metabolism in young people at risk for primary hypertension: the Dutch hypertension and offspring study. Hypertension. 1993;21:267–272
  30. Grobbee DE, Van Hooft IMS, Hofman A. Calcium metabolism and familial risk of hypertension. Semin Nephrol. 1995;15:512–518
  31. Sun G, Vasdev S, Martin GR, Gadag V, Zhang H. Altered calcium homeostasis is correlated with abnormalities of fasting serum glucose, insulin resistance, and {beta}-cell function in the Newfoundland population. Diabetes. 2005;54:3336–3339
  32. Haddy FJ. Roles of sodium, potassium, calcium, and natriuretic factors in hypertension. Hypertension. 1991;18:179–183
  33. Resnick L. The cellular ionic basis of hypertension and allied clinical conditions. Prog Cardiovasc Dis. 1999;42:1–22
  34. Sanchez M, de la Sierra A, Coca A, Poch E, Giner V, Urbano-Marquez A. Oral calcium supplementation reduces intraplatelet free calcium concentration and insulin resistance in essential hypertensive patients. Hypertension. 1997;29:531–536
  35. Halkin H, Modan M, Shefi M, Almog S. Altered erythrocyte and plasma sodium and potassium in hypertension, a facet of hyperinsulinemia. Hypertension. 1988;11:71–77
  36. Paolisso G, Barbagallo M. Hypertension, diabetes mellitus, and insulin resistance: the role of intracellular magnesium. Am J Hypertens. 1997;10:346–355
  37. Resnick LM, Gupta RK, Gruenspan H, Alderman MH, Laragh JH. Hypertension and peripheral insulin resistance. Possible mediating role of intracellular free magnesium. Am J Hypertens. 1990;3:373–379
  38. Resnick LM, Gupta RK, Gruenspan H, Laragh JH. Intracellular free magnesium in hypertension: relation to peripheral insulin resistance. J Hypertens Suppl. 1988;6:S199–S201
  39. Resnick LM, Gupta RK, Sosa RE, Corbett ML, Sealey JE, Laragh JH. Effects of altered dietary calcium intake in experimental hypertension: role of intracellular free magnesium. J Hypertens Suppl. 1986;4:S182–S185
  40. Resnick LM, Gupta RK, Laragh JH. Intracellular free magnesium in erythrocytes of essential hypertension: relation to blood pressure and serum divalent cations. Proc Natl Acad Sci U S A. 1984;81:6511–6515
  41. Chen HS, Hwu CM, Kwok CF, Shih KC, Hsiao LC, Lee SH, et al. Insulin sensitivity in normotensive offspring of hypertensive parents. Horm Metab Res. 2000;32:110–114
  42. Guo X, Cheng S, Taylor KD, Cui J, Hughes R, Quinones MJ, et al. Hypertension genes are genetic markers for insulin sensitivity and resistance. Hypertension. 2005;45:799–803
  43. Pazarloglou M, Spaia S, Pagkalos E, Ioannidis H, Askepidis N, Varyemezis V. Evaluation of insulin resistance and sodium sensitivity in normotensive offspring of hypertensive individuals. Am J Kidney Dis. 2007;49:540–546
  44. Winnicki M, Bonso E, Dorigatti F, Longo D, Zaetta V, Mattarei M, et al. Effect of body weight loss on blood pressure after 6 years of follow-up in stage 1 hypertension. Am J Hypertens. 2006;19:1103–1109
  45. Shankar A, Klein R, Klein BE, Nieto FJ. The association between serum uric acid level and long-term incidence of hypertension: population-based cohort study. J Hum Hypertens. 2006;20:937–945
  46. Jossa F, Farinaro E, Panico S, et al. Serum uric acid and hypertension: the Olivetti heart study. J Hum Hypertens. 1994;8:677–681
  47. Feig DI, Kang DH, Nakagawa T, Mazzali M, Johnson RJ. Uric acid and hypertension. Curr Hypertens Rep. 2006;8:111–115
  48. Murabito JM, Nam BH, D'Agostino S, Lloyd-Jones DM, O'Donnell CJ, Wilson PWF. Accuracy of offspring reports of parental cardiovascular disease history: the Framingham Offspring Study. Ann Intern Med. 2004;140:434–440
  49. Safar ME, Frohlich ED. The arterial system in hypertension. A prospective view. Hypertension. 1995;26:10–14

 Conflict of interest: none.

PII: S1933-1711(08)00184-8

doi: 10.1016/j.jash.2008.10.002

Journal of the American Society of Hypertension
Volume 3, Issue 2 , Pages 141-149 , March 2009

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