Journal of the American Society of Hypertension
Volume 2, Issue 5 , Pages 307-317, September 2008

Alcohol and hypertension: a review

  • Arthur L. Klatsky, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, Kaiser Permanente Medical Care Program, Oakland, California, USA
    • Division of Research, Kaiser Permanente Medical Care Program, Oakland, California, USA
    • Corresponding Author InformationCorresponding Author: Arthur L. Klatsky, MD, Kaiser Permanente Medical Center, 280 West MacArthur Boulevard, Oakland, California 94611. Tel: 510-752-6538; fax: 510-752-7456
  • ,
  • Erica Gunderson, PhD

      Affiliations

    • Division of Research, Kaiser Permanente Medical Care Program, Oakland, California, USA

Received 5 December 2007; accepted 25 March 2008. published online 24 June 2008.

Abstract 

In recent decades alcohol use has joined other correlates of hypertension (HTN), such as obesity and salt intake, as a major research focus about HTN risk factors. In cross-sectional and prospective epidemiologic studies, higher blood pressure (BP) has consistently been found among persons reporting usual daily intake of three standard-sized drinks or more. Although definitive mechanisms have not been established, several aspects of the data, including short and intermediate term experiments, suggest a causal relationship. Heavier drinking may, in fact, be the commonest cause of reversible HTN, and reduction of heavy alcohol intake plays an important public health role in HTN management. Additional to the mechanism, unresolved issues about the alcohol-BP relationship include whether there is a threshold dosage of alcohol for association with HTN, the sequelae of alcohol-associated HTN and the roles of interactions with gender, ethnicity, other lifestyle traits, drinking pattern, and choice of beverage. This article reviews these areas and includes new data about the beverage choice aspect.

Keywords: High blood pressure, risk factors, epidemiology, alcohol drinking

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 Conflict of interest: none.

 Portions of the material in this article include research supported by the Alcoholic Beverage Medical Research Foundation, Inc, Baltimore, Maryland, the Community Service Program of The Kaiser Permanente Medical Care Program, and by the Robert Wood Johnson Foundation.

PII: S1933-1711(08)00045-4

doi:10.1016/j.jash.2008.03.010

Journal of the American Society of Hypertension
Volume 2, Issue 5 , Pages 307-317, September 2008