Journal of the American Society of Hypertension
Volume 2, Issue 3 , Pages 158-164 , May 2008

Exaggerated exercise blood pressure response is related to tissue Doppler imaging estimated diastolic dysfunction in the early stages of hypertension

  • Costas Tsioufis, MD

      Affiliations

    • Department of Cardiology, Hippokration Hospital, Athens, Greece
    • Corresponding Author InformationCorresponding author: Costas Tsioufis, MD, 43, Agias Marinas Street, Melissia 15127, Athens, Greece. Tel: + 30 210 6131393; fax: + 30 210 7704802.
  • ,
  • Dimitris Chatzis, MD

      Affiliations

    • Department of Cardiology, Hippokration Hospital, Athens, Greece
  • ,
  • Dimitris Tsiachris, MD

      Affiliations

    • Department of Cardiology, Hippokration Hospital, Athens, Greece
  • ,
  • Vicky Katsi, MD

      Affiliations

    • Department of Cardiology, Hippokration Hospital, Athens, Greece
  • ,
  • Kostas Toutouzas, MD

      Affiliations

    • First Cardiology Clinic, University of Athens, Hippokration Hospital, Athens, Greece
  • ,
  • Dimitris Tousoulis, MD

      Affiliations

    • First Cardiology Clinic, University of Athens, Hippokration Hospital, Athens, Greece
  • ,
  • Ioannis Vlasseros, MD

      Affiliations

    • Department of Cardiology, Hippokration Hospital, Athens, Greece
  • ,
  • Christodoulos Stefanadis, MD

      Affiliations

    • First Cardiology Clinic, University of Athens, Hippokration Hospital, Athens, Greece
  • ,
  • Ioannis Kallikazaros, MD

      Affiliations

    • Department of Cardiology, Hippokration Hospital, Athens, Greece

Received 20 August 2007 ,Accepted 14 November 2007.

References 

  1. Leitschuh M, Cupples LA, Kannel W, Gagnon D, Chobanian A. High-normal blood pressure progression to hypertension in the Framingham Heart Study. Hypertension. 1991;17:22–27
  2. Miyai N, Arita M, Morioka I, Miyashita K, Nishio I, Takeda S. Exercise BP response in subjects with high-normal BP (Exaggerated blood pressure response to exercise and risk of future hypertension in subjects with high-normal blood pressure). J Am Coll Cardiol. 2000;36:1626–1631
  3. Singh JP, Larson MG, Manolio TA, O'Donnell CJ, Lauer M, Evans JC, et al. Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. Circulation. 1999;99:1831–1836
  4. Jae SY, Fernhall B, Heffernan K, Kang M, Lee MK, Choi YH, et al. Exaggerated blood pressure response to exercise is associated with carotid atherosclerosis in apparently healthy men. J Hypertens. 2006;24:881–887
  5. Sung J, Ouyang P, Silber HA, Bacher AC, Turner KL, DeRegis JR, et al. Exercise blood pressure response is related to left ventricular mass. J Hum Hypertens. 2003;17:333–338
  6. Pierson LM, Bacon SL, Sherwood A, Hinderliter AL, Babyak M, Gullette E, et al. Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients. J Hypertens. 2004;22:399–405
  7. Olsen MH, Wachtell K, Hermann KL, Bella JN, Andersen UB, Petersen HD, et al. Maximal exercise capacity is related to cardiovascular structure in patients with longstanding hypertension (A LIFE substudy). Am J Hypertens. 2001;14:1205–1210
  8. Sung J, Silber HA, Fleg JL, Kelemen MD, Turner KL, Bacher AC, et al. Exaggerated exercise blood pressure is related to impaired endothelial vasodilator function. Am J Hypertens. 2004;17:314–320
  9. Slama M, Susic D, Varagic J, Frohlich ED. Diastolic dysfunction in hypertension. Curr Opin Cardiol. 2002;17:368–373
  10. Angeja BD, Grossman W. Evaluation and management of diastolic heart failure. Circulation. 2003;107:659–663
  11. Leite-Moreira F. Current perspectives in diastolic dysfunction and diastolic heart failure. Heart. 2006;92:712–718
  12. Maurer MS, Spevack D, Burkhoff D, Kronzon I. Diastolic dysfunction (Can it be diagnosed by Doppler echocardiography?). J Am Coll Cardiol. 2004;44:1543–1549
  13. Pai RG, Gill KS. Amplitudes, durations and timings of apically directed left ventricular myocardial velocities: their normal pattern and coupling to ventricular filling and ejection. J Am Soc Echocardiogr. 1998;11:105–111
  14. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7th Report. JAMA. 2003;289:2560–2572
  15. Cifkova R, Erdine S, Fagard R, Farsang C, Heagerty AM, Kiowski W, et al. ESH/ESC Hypertension Guidelines Committee Practice guidelines for primary care physicians: 2003 ESH/ESC hypertension guidelines. J Hypertens. 2003;10:1779–1786
  16. Tsioufis C, Stefanadis C, Antoniadis D, Kallikazaros I, Zambaras P, Pitsavos C, et al. Absence of any significant effects of circadian blood pressure variations on carotid artery elastic properties in essential hypertensive subjects. J Hum Hypertens. 2000;14:813–818
  17. Tsioufis C, Chatzis D, Dimitriadis K, Stougianos P, Kakavas A, Vlasseros I, et al. Left ventricular diastolic dysfunction is accompanied by increased aortic stiffness in the early stages of essential hypertension: a TDI approach. J Hypertens. 2005;23:1745–1750
  18. Rivas-Gotz C, Khoury DS, Manolios M, Rao L, Kopelen HA, Nagueh SF. Time interval between onset of mitral inflow and onset of early diastolic velocity by tissue Doppler: a novel index of left ventricular relaxation: experimental studies and clinical application. J Am Coll Cardiol. 2003;42:1463–1470
  19. Fletcher G, Balady G, Froelicher V, Hartley LH, Haskel WL, Pollock ML. Exercise standards (Statement for healthcare professionals from the American Heart Association Writing Group). Circulation. 1995;91:580–615
  20. Lauer MS, Levy D, Anderson KM, Plehn JF. Is there a relationship between exercise blood pressure response and left ventricular mass? (The Framingham Heart Study). Ann Intern Med. 1992;116:203–210
  21. Benbassat J, Froom P. Blood pressure response to exercise as a predictor of hypertension. Arch Intern Med. 1986;146:2053–2055
  22. Bitigen A, Türkyılmaz E, Barutcu I, Kahveci G, Tanboga IH, Aung SM, et al. Aortic elastic properties in patients with hypertensive response to exercise. Circ J. 2007;71:727–730

 Conflict of interest: none.

PII: S1933-1711(07)00244-6

doi: 10.1016/j.jash.2007.11.002

Journal of the American Society of Hypertension
Volume 2, Issue 3 , Pages 158-164 , May 2008