Journal of the American Society of Hypertension
Volume 1, Issue 5 , Pages 296-301 , September 2007

Mentors, role models, and matters of the heart

  • Edward D. Frohlich, MD, MACP, FACC, FAHA

      Affiliations

    • Corresponding Author InformationCorresponding author: Edward D. Frohlich, MD, MACP, FACC, FAHA, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, Louisiana 70121. Tel: 504-842-3700; fax: 504-842-3258.

References 

  1. Frohlich ED, Robert P, Grant MD. Am J Cardiol. 2003;91:646–648
  2. Frohlich ED. Memoriam. In:  Edward D,  Freis MD editor. Hypertension. 45:2005;p. 825–827
  3. Freis ED. Hemodynamics of hypertension. Physiol Rev. 1960;40:27–54
  4. Tarazi RC, Miller A, Frohlich ED, Dustan HP. Electrocardiographic changes reflecting left atrial abnormality in hypertension. Circulation. 1966;34:818–822
  5. Tarazi RC, Frohlich ED, Dustan HP. Left atrial abnormality and ventricular pre-ejection period in hypertension. Dis Chest. 1969;55:214–218
  6. Frohlich ED, Tarazi RC, Dustan HP. Clinical-physiological correlations in the development of hypertensive heart disease. Circulation. 1971;44:446–455
  7. Dunn FG, Chandraratna P, de Carvalho JGR, Basta LL, Frohlich ED. Pathophysiologic assessment of hypertensive heart disease with echocardiography. Am J Cardiol. 1977;39:789–795
  8. Frohlich ED. The First Irvine H (Page lecture: the mosaic of hypertension; past, present, and future). J Hypertens. 1988;6(suppl 4):S2–S11
  9. Frohlich ED, Dustan HP, Page IH. Hyperdynamic beta-adrenergic circulatory state. Arch Intern Med. 1966;117:614–619
  10. Dustan HP, Tarazi RC, Frohlich ED. Functional correlates of plasma renin activity in hypertensive patients. Circulation. 1970;41:555–567
  11. Trippodo NC, Frohlich ED. Controversies in cardiovascular research: similarities of genetic (spontaneous) hypertension (Man and rat). Circ Res. 1981;48:309–319
  12. Pfeffer MA, Frohlich ED. Hemodynamic and myocardial function in young and old normotensive and spontaneously hypertensive rats. Circ Res. 1973;32:28–38
  13. Pfeffer MA, Pfeffer JM, Frohlich ED. Pumping ability and of the hypertrophying left ventricle of the spontaneously hypertensive rat. Circ Res. 1976;38:423–429
  14. Pfeffer MA, Ferrell BA, Pfeffer JM, Weiss AK, Fishbein MC, Frohlich ED. Ventricular morphology and pumping ability of exercised spontaneously hypertensive rats. Am J Physiol. 1978;235:H193–H199
  15. Pfeffer JM, Pfeffer MA, Fishbein MC, Frohlich ED. Cardiac function and morphology with aging in the spontaneously hypertensive rat. Am J Physiol. 1979;237:H461–H468
  16. Frohlich ED. Risk mechanisms in hypertensive heart disease. Hypertension. 1999;34:782–789
  17. Frohlich ED, Arthur C. Corcoran Memorial Lecture: influence of nitric oxide and angiotensin II on renal involvement in hypertension. Hypertension. 1997;29:188–193
  18. Frohlich ED. Target organ involvement in hypertension: a realistic promise of prevention and reversal. Med Clin North Am. 2004;88:209–221
  19. Zhou X, Matavelli LC, Frohlich ED. Uric acid: its relationship to renal hemodynamics and the renal renin-angiotensin system. Curr Hypertens Rep. 2006;8:120–124
  20. Frohlich ED. Uric acid: a risk factor for coronary heart disease. JAMA. 1993;270:378–379
  21. Frohlich ED. Promise of prevention and reversal of target organ involvement in hypertension. JRAAS. 2001;2(1):4–9
  22. Frohlich ED. A renewed call to mentor. Hypertension. 2000;36:309–311
  23. Frohlich ED, Varagic J. The role of sodium in hypertension is more complex than simply elevating arterial pressure. Nat Clin Pract Cardiovasc Med. 2004;1:24–30
  24. Ahn J, Varagic J, Slama M, Susic D, Frohlich ED. Cardiac structural and functional responses to salt loading in SHR. Am J Physiol (Heart Circ Physiol). 2004;287:H767–H772
  25. Varagic J, Frohlich ED. Hypertension and multifactorial role of salt. Lab Med. 2005;36:2–5
  26. Varagic J, Frohlich ED, Diez J, Susic D, Ahn J, Gonzalez A, et al. Myocardial fibrosis, impaired coronary hemodynamics, and biventricular dysfunction in salt-loaded SHR. Am J Physiol Heart Circ Physiol. 2006;290:H1503–H1509
  27. Matavelli LC, Zhou X, Varagic J, Susic D, Frohlich ED. Salt-loading produces severe renal hemodynamic dysfunction independent of arterial pressure in spontaneously hypertensive rats. Am J Physiol Circ Physiol. 2007;292:H814–H819
  28. Frohlich ED. The salt conundrum: a hypothesis. Hypertension. 2007;50:161–166

 Conflict of interest: none.

PII: S1933-1711(07)00130-1

doi: 10.1016/j.jash.2007.06.002

Journal of the American Society of Hypertension
Volume 1, Issue 5 , Pages 296-301 , September 2007

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