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Journal of the American Society of Hypertension
Volume 1, Issue 3
, Pages 164-168
, May 2007
Molecular mechanism of juxtaglomerular cell hyperplasia: a unifying hypothesis
References
- . The morphology of juxtaglomerular cell hyperplasia and hypertrophy in normotensive rats and monkeys given an angiotensin II receptor antagonist. Toxicol Pathol. 1995;23:606–619
- LXRα functions as a cAMP-responsive transcriptional regulator of gene expression. Proc Natl Acad Sci U S A. 2000;97:8513–8518
- Identification of a novel set of genes regulated by a unique liver X receptor-alpha-mediated transcription mechanism. J Biol Chem. 2003;278:15252–15260
- Liver X receptors alpha and beta regulate renin expression in vivo. J Clin Invest. 2005;115:1913–1922
- . Regulation of renin: new evidence from cultured cells and genetically modified mice. J Mol Med. 2000;78:130–139
- A Pit-1 binding site in the human renin gene promoter stimulates activity in pituitary, placental and juxtaglomerular cells. Kidney Int. 1994;46:1513–1515
- . Transcriptional induction of the human renin gene by cyclic AMP requires cyclic AMP response element-binding protein (CREB) and a factor binding a pituitary-specific trans-acting factor (Pit-1) motif. Biochem J. 1996;316(Pt 1):107–113
- . Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP (Identification of an inhibitory protein that binds nuclear transcriptional factor). J Biol Chem. 1991;266:16247–16254
- . Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression. J Clin Invest. 1993;92:1805–1811
- . Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes. Proc Natl Acad Sci U S A. 1989;86:56–59
- Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. J Biol Chem. 2001;276:45530–45538
- . Transcriptional regulation of renin: an update. Hypertension. 2005;45:3–8
- Mechanism of cAMP regulation of renin gene transcription by proximal promoter. J Clin Invest. 1994;94:1959–1967
- . Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol. 2001;2:599–609
- . Structural analysis of the prolactin gene suggests a separate origin for its 5′ end. Nature. 1982;297:603–606
- . Hormonal regulation of plasminogen activator mRNA production in porcine kidney cells. Cell. 1983;32:1181–1190
- . Isolation and characterization of the rat tyrosine aminotransferase gene. Proc Natl Acad Sci U S A. 1984;81:1346–1350
- . Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes. Proc Natl Acad Sci U S A. 1992;89:885–889
- Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo. Circ Res. 1999;84:1059–1066
- . In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer. J Clin Invest. 1995;96:1230–1237
- Expression of a renin/GFP transgene in mouse embryonic, extra-embryonic, and adult tissues. Physiol Genomics. 2000;4:75–81
- . c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol. 2001;11:558–568
- . N-myc oncogene expression in porcine renal development and oncogenesis. Pediatr Res. 1991;29:268–271
- . Defining the specific physiological requirements for c-Myc in T cell development. Nat Immunol. 2001;2:307–315
- . Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo. Genes Dev. 1989;3:860–869
- . Changes in expression of members of the fos and jun families and myc network during terminal differentiation of human keratinocytes. Oncogene. 1995;11:1403–1407
- . c-Myc promotes differentiation of human epidermal stem cells. Genes Dev. 1997;11:2869–2882
- . Proteins of the c-Myc network: essential regulators of cell growth and differentiation. Adv Cancer Res. 1996;68:109–182
- N-myc can functionally replace c-Myc in murine development, cellular growth, and differentiation. Genes Dev. 2000;14:1390–1399
- . N-myc expression in the embryonic cochlea of the mouse. Hear Res. 1994;72:53–58
- . Two transient increases in c-Myc gene expression during neuroectodermal differentiation of mouse embryonal carcinoma cells. Oncogene. 1988;3:553–559
- . Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet. 2001;28:165–168
- Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct. J Biol Chem. 1990;265:19916–19922
- Nuclear hormone receptor LXRα mediates renin and early response gene expressions, and proliferation of juxtaglomerular As4.1 cells: A unifying molecular mechanism for JG cell hyperplasia. Hypertension. 2006;48:e74;(Abstract: Poster presented at 60th Annual Fall Conference and Scientific Sessions of the Council for High Blood Pressure Research in association with the Council on the Kidney in Cardiovascular Disease, American Heart Association. October 4–7, 2006. San Antonio, Texas, USA)
- . Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened. Dev Cell. 2004;6:719–728
- . Embryonic origin and lineage of juxtaglomerular cells. Am J Physiol Renal Physiol. 2001;281:F345–F356
- . Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes. Hypertension. 2006;48:1095–1102
- . Hydroxycholesterol or cyclic AMP upregulates the expression of renin in human mesenchymal stem cells (Abstract: Poster presented at Scientific Sessions 2006, American Heart Association. November 12–15, 2006. Chicago, Illinois, USA). Circulation. 2006;114(Suppl II):II–94
- . Stem cells in the kidney. Kidney Int. 2002;61:387–395
- . In search of adult renal stem cells. J Cell Mol Med. 2004;8:474–487
- Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol. 2004;15:1794–1804
- . The renal papilla is a niche for adult kidney stem cells. J Clin Invest. 2004;114:795–804
- Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues. Proc Natl Acad Sci U S A. 2005;102:3296–3300
This study was supported by the National Heart, Lung, and Blood Institute (Grant nos. R01 HL35610, HL58516, HL72010, and HL73219 [VJD]) and the Edna Mandel Foundation (VJD).Conflict of interest: none.
PII: S1933-1711(07)00059-9
doi: 10.1016/j.jash.2007.02.004
© 2007 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.
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Journal of the American Society of Hypertension
Volume 1, Issue 3
, Pages 164-168
, May 2007
