Journal of the American Society of Hypertension
Volume 1, Issue 3 , Pages 185-188, May 2007

Cardiovascular diseases, aging, and the gender gap in human longevity

  • Abraham Aviv, MD

      Affiliations

    • Dr. Aviv’s aging research is supported by the National Institutes of Health grants R01HL070137, R01AG20132, and R01AG021593 and by grants from The Healthcare Foundation of New Jersey.
    • Corresponding Author InformationCorresponding author: Abraham Aviv, MD, The Center of Human Development and Aging, Room F-464, MSB, The New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, Newark, New Jersey 07103. Tel: 973-972-5280; fax: 973-972-5576.

The Center of Human Development and Aging, The New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA

Received 14 December 2006; accepted 11 February 2007.

Abstract 

This study probes the biological meaning of the gender gap in longevity and its possible ramifications for the expression of cardiovascular diseases in human beings. It addresses the potential role of estrogen and the X chromosome in the longer life span of women than men in modern societies. In addition, it links features of the reproductive and post-reproductive periods with cardiovascular diseases and longevity in women.

Keywords: Fitness, chromosome, estrogen, menopause, evolution

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 Conflict of interest: none.

PII: S1933-1711(07)00056-3

doi:10.1016/j.jash.2007.02.002

Journal of the American Society of Hypertension
Volume 1, Issue 3 , Pages 185-188, May 2007

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