« Previous
Next »
Journal of the American Society of Hypertension
Volume 1, Issue 3
, Pages 189-199
, May 2007
Increased inflammatory biomarkers in hypertensive type 2 diabetic patients: improvement after angiotensin II type 1 receptor blockade
References
- . Vascular inflammation: a role in vascular disease in hypertension?. Curr Opin Nephrol Hypertens. 2003;12:181–187
- . Blood pressure and inflammation in apparently healthy men. Hypertension. 2001;38:399–403
- . Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin II-infused macrophage colony-stimulating factor-deficient mice (Evidence for a role in inflammation in angiotensin-induced vascular injury). Arterioscler Thromb Vasc Biol. 2005;25:2106–2113
- . Markers of inflammation and coronary artery disease. Med Sci Monit. 2002;8:RA5–RA12
- . Inflammation as a cardiovascular risk factor. Circulation. 2004;109(21 Suppl 1):II2–II10
- . The proinflammatory and hypercoagulable state of diabetes mellitus. Rev Cardiovasc Med. 2005;6:84–97
- . C-reactive protein and the risk of developing hypertension. JAMA. 2003;290:2945–2951
- . Effects of severe, uncontrolled hypertension on endothelial activation: soluble vascular cell adhesion molecule-1, soluble intercellular adhesion molecule-1 and von Willebrand factor. J Hypertens. 2002;20:871–877
- . von Willebrand factor, soluble P-selectin, and target organ damage in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). Hypertension. 2002;40:61–66
- . Soluble cell adhesion molecules in hypertensive concentric left ventricular hypertrophy. J Hypertens. 2002;20:1563–1569
- . Blood pressure, C-reactive protein, and risk of future cardiovascular events. Circulation. 2003;108:2993–2999
- High sensitivity C-reactive protein as an independent risk factor for essential hypertension. Am J Hypertens. 2003;16:429–433
- C-reactive protein as a predictor for incident diabetes mellitus among middle-aged men: results from the MONICA Augsburg cohort study, 1984-1998. Arch Intern Med. 2003;163:93–99
- Enhanced levels of platelet P-selectin and circulating cytokines in young patients with mild arterial hypertension. J Hypertens. 2005;23:995–1000
- . Association between prehypertension status and inflammatory markers related to atherosclerotic disease: the ATTICA Study. Am J Hypertens. 2004;17:568–573
- Single nucleotide polymorphisms in the interleukin-6 gene associated with blood pressure and atherosclerosis in a Japanese general population. Hypertens Res. 2005;28:35–41
- . Type 1 diabetes is associated with increased cyclooxygenase- and cytokine-mediated inflammation. Diabetes Care. 2005;28:1371–1375
- Low-grade inflammation, endothelial activation and carotid intima-media thickness in type 2 diabetes. J Intern Med. 2004;256:119–127
- The relationship of cardiovascular risk factors to microalbuminuria in older adults with or without diabetes mellitus or hypertension: the Cardiovascular Health Study. Am J Kidney Dis. 2004;44:25–34
- Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): Prospective Observational Study. BMJ. 2000;321:412–419
- . Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ. 1998;317:703–713
- Effects of candesartan cilexetil and enalapril on inflammatory markers of atherosclerosis in hypertensive patients with non-insulin-dependent diabetes mellitus. J Hypertens. 2005;23:435–444
- Effects of AT1 receptor antagonist losartan on sICAM-1 and TNF-alpha levels in uncomplicated hypertensive patients. Angiology. 2004;55:195–203
- . Effects of nifedipine GITS 20 mg or enalapril 20 mg on blood pressure and inflammatory markers in patients with mild-moderate hypertension. Blood Press Suppl. 2005;1:14–22
- Fosinopril decreases levels of soluble vascular cell adhesion molecule-1 in borderline hypertensive type II diabetic patients with microalbuminuria. Am J Hypertens. 1999;12:217–222
- Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients. J Am Coll Cardiol. 2003;42:905–910
- . Multiple actions of angiotensin II in hypertension: benefits of AT1 receptor blockade. J Am Coll Cardiol. 2003;42:911–913
- . Recent advances in vascular inflammation: C-reactive protein and other inflammatory biomarkers. Curr Opin Rheumatol. 2004;16:18–24
- . C-reactive protein as a predictor of total arteriosclerotic outcomes in type 2 diabetic nephropathy. Kidney Int. 2005;68:773–778
- . C-reactive protein and risk factors for peripheral vascular disease in subjects with type 2 diabetes mellitus. Diabet Med. 2004;21:336–341
- Angiotensin receptor blocker added to previous antihypertensive agents on arteries of diabetic hypertensive patients. Hypertension. 2006;48:271–277
- . Effects of diabetes and hypertension on macrophage infiltration and matrix expansion in the rat kidney. BMC Nephrol. 2005;6:6–8
- . Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans. Clin Immunol. 2005;117:152–160
- Elevated levels of interleukin-18 predict the development of type 2 diabetes: results from the MONICA/KORA Augsburg study, 1984-2002. Diabetes. 2005;54:2932–2938
- . Effects of losartan and simvastatin on monocyte-derived microparticles in hypertensive patients with and without type 2 diabetes mellitus. Clin Appl Thromb Hemost. 2004;10:133–141
- Association among plasma levels of monocyte chemoattractant protein-1, traditional cardiovascular risk factors, and subclinical atherosclerosis. J Am Coll Cardiol. 2004;44:1812–1818
- IL-18: relationship with anthropometry, body composition parameters, leptin and arterial hypertension. Horm Metab Res. 2006;38:507–512
- Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats. BMC Cardiovasc Disord. 2002;2:3–9
- Atherosclerosis Risk in Communities Study (Low-grade systemic inflammation and the development of type 2 diabetes: the Atherosclerosis Risk in Communities Study). Diabetes. 2003;52:1799–1805
- . Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis. Hypertension. 2001;38:581–587
- Effect of AT1 receptor antagonism on vascular and circulating inflammatory mediators in SHR: role of NF-kappaB/IkappaB system. Am J Physiol Heart Circ Physiol. 2005;288:H111–H115
- . Angiotensin II AT1 receptor blockade decreases brain artery inflammation in a stress-prone rat strain. Ann N Y Acad Sci. 2004;1018:345–350
- . Reactive oxygen species in vascular biology: implications in hypertension. Histochem Cell Biol. 2004;122:339–352
- . Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications (Emerging new therapeutical strategies). Curr Med Chem. 2005;12:267–275
- . Effects of enalapril and losartan on circulating adhesion molecules and monocyte chemotactic protein-1. Clin Sci (Lond). 2002;103:131–136
- . Effect of losartan in aging-related endothelial impairment. Am J Cardiol. 2002;89:562–566
- . Angiotensin II blockade is associated with decreased plasma leukocyte adhesion molecule levels in diabetic nephropathy. Diabetes Care. 2000;23:1031–1032
- Differential effects of short-term ace- and AT1-receptor inhibition on postischemic injury and leukocyte adherence in vivo and in vitro. Shock. 2000;13:190–196
- Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris (Results from the APSIS study. The Angina Prognosis Study in Stockholm). Atherosclerosis. 2000;148:179–188
- . Antioxidant activity of β-blockers: an effect mediated by scavenging reactive oxygen and nitrogen species?. Bioorg Med Chem. 2006;14:4568–4577
- Regression of carotid atherosclerosis by control of morning blood pressure peak in newly diagnosed hypertensive patients. Am J Hypertens. 2005;18:308–318
- . Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress. Curr Med Chem Cardiovasc Hematol Agents. 2005;3:133–148
- . Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial. Hypertension. 2006;48:73–79
This study was supported by an unrestricted grant from Novartis Pharmaceuticals Canada and by grants 44018 (to RMT) and 13570 (to ELS), as well as by a group grant to the Multidisciplinary Research Group on Hypertension, all from the Canadian Institutes for Health Research. CS and CDeC were supported in part by fellowships from the Italian Society of Hypertension. DHE was supported by a grant from the Deutsche Forschungsgemeinschaft. The authors would like to thank Mireille Kirouac, RN, for devoted follow-up of patients and blood sampling.Conflict of interest: none.
PII: S1933-1711(07)00039-3
doi: 10.1016/j.jash.2007.01.009
© 2007 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Journal of the American Society of Hypertension
Volume 1, Issue 3
, Pages 189-199
, May 2007
