Journal of the American Society of Hypertension
Volume 1, Issue 2 , Pages 135-144, March 2007

Blood pressure, cognitive dysfunction, and dementia

  • Hossein Eftekhari, MD
    • ,
  • Seth Uretsky, MD
    • ,
  • Franz H. Messerli, MD, FACC

      Affiliations

    • Corresponding Author InformationCorresponding author: Franz H. Messerli, MD, FACC, Director, Division of Hypertension, Department of Cardiology, St. Luke’s-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, 1000 Amsterdam Avenue, New York, New York 10019.

St. Luke’s-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA

Received 5 December 2006; accepted 16 January 2007.

Abstract 

With the aging of the population, the incidence and prevalence of cognitive disorders are increasing. Blood pressure plays an important role in the pathogenesis or clinical progression of stroke, vascular dementia, and Alzheimer’s disease. Data from different studies reveal that the uses of antihypertensive medications decrease the risk of dementia and cognitive dysfunction. Several studies also have demonstrated a relationship between hypotension, cognitive decline, and dementia. In this review we are trying to demonstrate the relationship between blood pressure and cognitive function and also the effect of antihypertensive medications on dementia and cognitive dysfunction.

Keywords: Blood pressure, dementia, cognition, antihypertensive therapy

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 Conflict of interest: none.

PII: S1933-1711(07)00015-0

doi:10.1016/j.jash.2007.01.003

Journal of the American Society of Hypertension
Volume 1, Issue 2 , Pages 135-144, March 2007

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